driving clinical outcomes

Two studies published in 2011 and 2017 analysed the outcomes of a lifestyle intervention via the Liva platform in a clinical setting. Both studies showed significant results of sustained weight loss after respectively 20 and 12 months of follow-up.

The first study was carried out by University of Southern Denmark in cooperation with Newcastle University. An average weight loss of 7.0 kg was observed after 20 months as a result of online consultations with a clinical dietitian after GP referral [1].

Read the study here (page 23).


The second study (an RCT trial backed by NHS in Durham and Darlington) was carried out by University of Newcastle and FUSE (The Centre For Transnational Research in Public Health). A weight loss of 5.4 kg for men with type 2 diabetes was observed after 12 months. In comparison, the control group lost 2.8 kg. [2]

Read the study here. 


In August 2017 the Journal of American Medical Association (JAMA) published an RCT study) carried out by professor Bente Klarlund Pedersen and her research group at Copenhagen University Hospital (Rigshospitalet), showing that diabetes can be rolled back though lifestyle change.

  • All participants received standard care with individual counselling and standardised, blinded, target-driven medical therapy.
  • The intervention group additionally received a lifestyle intervention: 5 to 6 weekly aerobic training sessions (30-60 minutes), of which 2 to 3 sessions were combined with resistance training and dietary plans.

Results were significant:

73.5% of participants in the intervention group were able to reduce their pharmaceutical usage and 56.4% discontinued medication. In the control group, receiving standard care, the numbers were significantly lower with:

26.4% being able to reduce pharmaceutical usage, and 14.7% discontinuing medication.

From baseline to 12-month follow-up, the mean HbA1c level changed from 6.65%to 6.34% in the intervention group and from 6.74% to 6.66% in the standard care group.

Read the study in JAMA here (abstract).



[1] Brandt CJ, Brandt V, Pedersen M, Glintborg D, Toubro S, Nielsen JB, et al. Long-Term Effect of Interactive Online Dietician Weight Loss Advice in General Practice (LIVA) Protocol for a Randomized Controlled Trial. International journal of family medicine. 2014;2014:245347.

[2] Haste A, Adamson AJ, McColl E, Araujo-Soares V, Bell R. Web-Based Weight Loss Intervention for Men With Type 2 Diabetes: Pilot Randomized Controlled Trial. JMIR Diabetes. 2017;2(2).

[3] Johansen MY, MacDonald CS, Hansen KB, Karstoft K, Christensen R, Pedersen M, et al. Effect of an Intensive Lifestyle Intervention on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial. JAMA : the journal of the American Medical Association. 2017;318(7):637-46.