A new Danish RCT study published by the Journal of American Medical Association (JAMA) shows that diabetes can be rolled back though lifestyle change.
The RCT study was carried out by professor Bente Klarlund Pedersen and her research group at Copenhagen University Hospital (Rigshospitalet).
- All participants received standard care with individual counselling and standardized, blinded, target-driven medical therapy.
- The intervention group additionally received a lifestyle intervention: 5 to 6 weekly aerobic training sessions (30-60 minutes), of which 2 to 3 sessions were combined with resistance training plus dietary plans.
Results were significant:
73.5% of participants in the intervention group were able to reduce their pharmaceutical usage and 56.4% discontinued medication. In the control group, receiving standard care, the numbers were significantly lower with:
26.4% being able to reduce pharmaceutical usage, and 14.7% discontinuing medication.
From baseline to 12-month follow-up, the mean HbA1c level changed from 6.65%to 6.34% in the intervention group and from 6.74% to 6.66% in the standard care group.
Johansen MY, MacDonald CS, Hansen KB, Karstoft K, Christensen R, Pedersen M, et al. Effect of an Intensive Lifestyle Intervention on Glycemic Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial. JAMA : the journal of the American Medical Association. 2017;318(7):637-46.